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https://hdl.handle.net/20.500.12394/5522
Título: | Endothelial dysfunction assessment by flow-mediated dilation in a high-altitude population |
Autor(es): | Calderón-Gerstein, W. S. López-Peña, A. Macha-Ramírez, R. Bruno-Huamán, A. Espejo-Ramos, R. Vílchez-Bravo, S. Ramírez-Breña, M. Damián-Mucha, M. Matos-Mucha, A. |
Palabras clave: | Endothelial dysfunction Vasoreactivity Brachial artery High altitude Flow-mediated vasodilation |
Editorial: | Universidad Continental |
Fecha de publicación: | sep-2017 |
Fecha disponible: | 28-may-2019 |
Cita bibliográfica: | Calderón, W., López, A., Macha, R., Bruno, A., Espejo, R., Vílchez, S., Ramírez, M., Damián, M., Matos, A. (2017). Endothelial dysfunction assessment by flow-mediated dilation in a high-altitude population. Vascular Health and Risk Management, 13(21), 421-426. https://doi.org/10.2147/VHRM.S151886 |
DOI: | 10.2147/VHRM.S151886 |
Resumen/Abstract: | Introduction: Endothelial function at high altitude has been measured only in populations that are genetically adapted to chronic hypoxia. The objective of this study was to evaluate endothelial dysfunction (ED) in a nongenetically adapted high-altitude population of the Andes mountains, in Huancayo, Peru (3,250 meters above sea level). Methods: Participants included 61 patients: 28 cases and 33 controls. The cases were subjects with hypertension, diabetes mellitus, obesity, or a history of stroke or coronary artery disease. Flow-mediated vasodilation (FMD) of the brachial artery was measured in the supine position, at noon, after 5 minutes of resting. The brachial artery was identified above the elbow. Its basal diameter was measured during diastole, and FMD was tested after 5 minutes of forearm ischemia. Intima–media complex in the right carotid artery was also determined. An increase in the artery’s baseline diameter <10% indicated a positive test. Endothelium-independent vasodilation was evaluated with sublingual nitrate administration. The intima–media complex in the right carotid artery was also measured. |
Descripción: | p. 421-426 |
Incluido en: | https://www.dovepress.com/endothelial-dysfunction-assessment-by-flow-mediated-dilation-in-a-high-peer-reviewed-article-VHRM |
Acceso: | Acceso abierto |
Fuente: | Universidad Continental |
Aparece en las colecciones: | Artículos Científicos |
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